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SV - Several Post-doctoral Fellowships (5) in Molecular/Cellular Neurobiolgoy, Chemical Biology, and Proteomics and Biomarkers Discovery
Several post-doctoral positions are available immediately in the Laboratory of Molecular and Chemical Biology of Neurodegeneration (http://lashuel-lab.epfl.ch/)at the Swiss Federal Institute of Technology in Lausanne (EPFL), Switzerland (www.epfl.ch).The selected candidates will work on interdisciplinary and translational projects aimed at elucidating the molecular determinants and cellular pathways that trigger and regulate protein misfolding, aggregation, and propagation in cellular and animal models of neurodegenerative diseases.
Cellular and Animal Modeling of Neurodegenerative Diseases:
The desired applicant must have a Ph.D. degree and strong track record of accomplishment in one of the following fields: molecular and/or cellular neurobiology and/or the development and characterization of cellular and animal models of neurological disorders. Candidates with experience in working with models of Parkinson’s disease, viral vectors, DNA repair pathways, protein homeostasis and degradation pathways are especially encouraged to apply, although experience in the field of neurodegeneration is not a must.
Organic Synthesis and Chemical Biology:
The applicant must have a Ph.D. degree in organic/bioorganic chemistry with a strong publication record and demonstrated experience in at least two of the following areas; 1) organic synthesis; 2) peptide and chemical synthesis and semisynthesis of proteins; 3) synthesis of unnatural amino acids novel probes to study protein structure and function. Additional experience in protein biophysics and protein biochemistry is a plus, but not a requirement.
Mass Spectrometry and Biomarkers Discovery:
The applicant must have a Ph.D. degree in Biochemistry or Chemistry with a strong publication record and demonstrated experience in 1) the development of immunoassays for protein quantifications and/or 2) targeted and quantitative mass spectrometry using LC-MS/MS and triple quadrupole MS systems, immunoprecipitation (IP), as well as conventional biochemical techniques for the analysis of human samples including plasma and CSF. Additional experience in protein biochemistry is a plus.
We are looking for highly motivated and enthusiastic scientists with a Ph.D. degree in Chemistry, Biochemistry or Chemical Biology. Candidates with experience and demonstrated track record in chemical synthesis and semisynthesis of proteins and working at the interface of chemistry and biology are encouraged to apply. Very good writing and communication skills are important, and the ability to be a team player and interact with several groups is a must.
The qualified candidate will benefit from working with a very dynamic and multidisciplinary group in a highly collaborative and stimulating environment and access to state of the art laboratories and core-facilities and a competitive salary
For more information about our group, please visit our website and review our recent publications at http://www.ncbi.nlm.nih.gov/pubmed/?term=Lashuel
The Lashuel Laboratory:http://lashuel-lab.epfl.ch/
School of Life Sciences:http://sv.epfl.ch
Platforms and Core Facilities:http://sv.epfl.ch/platforms
Interested applicant should submit a letter of interest, curriculum vitae and the names and addresses of three references to Prof. Hilal Lashuel.
Prof. Hilal Lashuel
Swiss Federal Institute of Technology (EPFL)
SV-BMI-LMNN, AI 2151 Station 19 CH-1015 Lausanne , Switzerland