173 days ago on careers.amgen.com

Senior Manager Economic Modeling

AMGEN Switzerland AG

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Senior Manager Economic Modeling

Health Economics Senior Managers at Amgen Economic Modeling Center of Excellence

Amgen discovers, develops and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science’s promise by bringing novel medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. With a broad and deep pipeline of potential new medicines, Amgen is committed to advancing science to dramatically improve people’s lives. Amgen is committed to promoting and maintaining an inclusive, high-performing culture where all team members embrace and leverage each others‘ talents and backgrounds, nourish innovative thinking, achieve their full potential, and contribute to Amgen’s success. Our commitment to diversity is articulated in our core values and reflected in every part of our organization.

We are currently seeking candidates to join the Amgen Economic Modeling Center of Excellence based in Zug, Switzerland. We work in cross-functional teams developing and supporting product value strategy focusing on evidence-based economic modeling throughout the product life-cycle. The activities of the Economic Modeling Center of Excellence include early modeling for strategic input to development design, pricing strategy, core models and local model adaptations for Health Technology Assessment (HTA) and price and reimbursement submissions, as well as tools supporting field-based key account value communication.

The successful candidates will take the role as economic modeling lead with KEY RESPONSIBILITIES to:

• Lead, manage and coach a team of economic modelers.
• Lead development and updates of core global cost-effectiveness and budget impact models in collaboration with cross-functional local, regional and global teams.
• Provide input to Global Value Dossiers and Value Stories development and updates.
• Lead local economic model adaptations to address local requirements, being responsible for project management, content and execution.
• Provide input to design and interpretation of evidence generation studies.
• Interpret clinical studies results and plan additional statistical analyses needed for core models and local adaptations, including indirect treatment comparisons.
• Present, discuss and re-analyze model results.
• Report the economic section of HTA pricing and reimbursement submissions.
• Support timely and effective communication to HTA and reimbursement authorities.
• Lead and support publications of core global and local economic models.


• MSc or PhD in Health Economics with a background in economics or in a quantitative field (such as (bio)statistics, epidemiology or engineering).
• 6+ (with MSc) 3+ (with PhD) years relevant work experience in the pharmaceutical industry, consultancy, academia or reimbursement agencies.
• Previous experience in oncology and/or cardiovascular disease areas.
• Previous experience managing direct reports is preferred.
• Strong experience in developing core and local adaptations of cost-effectiveness and budget impact models.
• Strong statistical skills, in particular deep knowledge of advanced survival analyses.
• Strong Excel skills and experience using Visual Basic, and software such as TreeAge Pro, R, SAS, Stata or WinBUGS for model development and data analysis.
• Strong analytical, communication and project management skills.
• Fluency in English.