38 days ago on aofoundation.org

​ Early Stage Researcher PhD Position ​

AO Foundation

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 Please refer to JobSuchmaschine in your application

​ Early Stage Researcher PhD Position ​


AO Foundationis a medically-guided, non-profit organization led by an international group of surgeons specialized in the treatment of trauma, and disorders of the musculoskeletal system. Founded in 1958 by 13 visionary surgeons, AO fosters one of the most extensive networks of currently over 16,000 surgeons, operating-room personnel, and scientists in more than 100 countries. For more information, please visit

Early Stage Researcher PhD Position

We are seeking an enthusiastic and motivated candidate for a 36 months position within the Disc/Cartilage team in the
Musculoskeletal Regeneration Programof the AO Research Institute Davos.

The Project
TargetCaRe is a Marie Sklodowska-Curie Innovative Training Network (MSCA-ITN) on targeting cartilage regeneration in joints and intervertebral disc diseases in the Horzion2020 programme of the European Union (
https://www.targetcare.eu). In total, 15 Early Stage Researchers (ESRs) are appointed by the TargetCaRe consortium for 36 months each.

Job Requirements
The aim of this project is to evaluate the efficacy of activated nanocarriers for intervertebral disc (IVD) regeneration using an organ culture model in a bioreactor system. The PhD candidate will investigate the regenerative and anti-inflammatory effects of implanted nanocarriers containing bioactive agents under relevant loading conditions. Different analysis methods will be used, including biochemical, cell and molecular biological analyses such as cell viability, gene expression, protein synthesis, histology and immunohistochemistry, and imaging techniques.

An ideal ESR PhD candidate will have a Master degree with excellent marks from his/her previous studies and courses along with experience in the field of cell and molecular biology or bioengineering. Practical experience in cell/tissue culture methodology is required. Experience in using biological, biochemical, and imaging analysis techniques (e.g. protein and gene expression analysis; microscopy) is also desirable. The candidate must be enthusiastic and excited about the field of regenerative medicine, while excellent written and oral communication skills are desirable.

MSCA-ITN offers an attractive salary and working conditions. A unique feature of MSCA-ITN is that ESR PhD students will be given the opportunity to perform at least two secondments of about 3 months each at the facilities of other consortium members. ESR PhD students will benefit from a dedicated training program in the various fields of expertise of the consortium partners.

More information on MSCA-ITN

Your application

To apply for this position, send your CV and motivation letter to targetcare@erasmusmc.nl. Please state the vacancy reference (Targetcare ESR #10) in the subject line. After eligibility screening, your application will be forwarded to Prof. Mauro Alini, AO Research Institute Davos, for further evaluation.

AO Foundation

AO Research Institute Davos, Switzerland

Musculoskeletal Regeneration Program

Head:Prof. Mauro Alini, PhD

Investigator:Sibylle Grad, PhD

Clavadeler Strasse 8

7270 Davos