130 days ago on roche.com

Translational Medicine Leader - Neuroscience Rare Diseases

Roche AG

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Translational Medicine Leader - Neuroscience Rare Diseases

Translational Medicine Leader – Neuroscience Rare Diseases

Switzerland, Basel-Town, Basel

The TML – Rare Diseases will provide clinical development project leadership in Neuromuscular/Neurological Rare Diseases and contributes to broad clinical strategy across the Rare Disease portfolio.  Represents clinical science on discovery teams and external joint research teams to ensure alignment on strategy between pharma development and discovery, to support target and clinical candidate selection and to provide guidance on benefit/risk assessment and risk mitigation activities.
Ensures the timely development of the rare disease clinical development plan including the biomarker strategy and Proof of Concept (PoC) scenarios to ensure fast and efficient assessment of the clinical candidate and fact-based go/no go decisions for the molecule or the program.  Develops protocols for PoC and confirmatory studies and supports protocol development for experimental medicine and clinical pharmacology studies .  Ensures that assigned clinical programs are of the utmost scientific quality considering scientific, regulatory, business, cost and time perspectives.
Assumes medical leadership for projects in throughout rare disease asset development and is accountable for clinical deliverables at the project level.  Leads the clinical team and may have one or more direct reports.
  • Proposes, establishes and leads external collaborations relevant to assigned project and to disease area strategy; participates in due diligences
  • Presents clinical development plan or elements thereof to management boards; organizes scientific advisory board meetings
  • Leads the global development team during the confirmatory phase:  may define and lead exploratory translational science activities to support life cycle team and/or disease area strategies
  • Contributes to aspects of disease area strategy planning
  • Maintains external scientific presence through high quality publications in peer-reviewed journals  or oral presentations in international congress
  • Who you are
    You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point.
    An MD or MD/PhD with clinical training in neurology, neuromuscular medicine, neurogenetics or paediatric neurology or other relevant field along with a few years of experience is required.
    • Proven track record in conducting and directing original, innovative, clinical and/or translational research as demonstrated by academic publications or accomplishments in the pharmaceutical industry
    • Experience in drug development is preferred
    • Demonstrated track record of providing clinical leadership to rare disease programs preferred
    • Leadership and managerial skills, including motivating, delegating, mentoring, coaching, line management, high level of business awareness and excellent planning and organizational skills
    • Strong verbal and written communication skills in English are required
  • Who we are
    Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 8,500 people from approximately 90 countries work in Basel, which is one of Roche`s largest sites. Read more.

    Roche is an equal opportunity employer.
  • Job facts
    • Location Switzerland, Basel-Town, Basel
    • Function Research
    • Subfunction Other Research
    • Schedule Full-time
    • Job level Individual Contributor
    • Job type Regular Employee
    • Division Roche Pharmaceuticals
    • Posted since 2017/11/08
    • Job-ID 3427040622
  • Get in touch
    Recruiting Team Switzerland +41 61 682 25 50