19 days ago on roche.com

Translational Medicine Leader (TML)

Roche AG

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Translational Medicine Leader (TML)

Translational Medicine Leader (TML)

Switzerland, Zurich, Zurich

Switzerland, Basel-Town, Basel

The Translational Medical Leader (TML) is a core member of the well-established Oncology Translational Medicine Organization, working in the Translational Science Group. The TML leads the exploratory medicine strategy for multiple early oncology drug assets. He / She is the key medical expert on the early Global Discovery Team and ensures alignment of the development strategy with the overall Roche/GNE disease area strategy. The TML owns and drives the exploration of clinical-translation data to design the clinical development strategy for new compounds (both small and large molecules).


The TML:

  • Shapes the hypotheses to be tested pre-clinically to facilitate entry into human clinical phase
  • Represents the main interface between Oncology Translational Medicine and Oncology Discovery for project- and program-related activities
  • Supports target and clinical candidate selection, be accountable for the design and the clinical and scientific content of experimental medicine studies to evaluate and validate targets
  • Proposes, establishes and leads external collaborations to address strategic and tactical needs
  • Works with the Biomarker Experimental Medicine Leader to develop biomarker strategies
  • Reports to Head of Translational Science
  • Who you are
    You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point.

    As the ideal candidate, you bring solid experience in clinical oncology and overall knowledge of the broad research and drug development process in oncology. You are medically qualified (MD), ideally combined with a PhD. You have a proven record of scientific achievement with significant experience in drug development documented by presentations and publications in peer reviewed Journals


    Additionally, you have the following skills/ expertise:

    • Patient-related clinical experience as investigator on Phase I/II studies
    • Industry experience (minimum 2-3 years) preferred
    • Enjoy thinking strategically beyond current standard of care and at the same time able to work hands on
    • A positive mindset and understanding of the challenges and uncertainty of early medical research
    • Proactive, very flexible attitude, and you can adapt easily to change
    • Excellent communication skills and fluency in English
    • An independent working style, and you are also a strong team player
    • You have the ability to independently develop the clinical strategy for exploratory development
    • You work as experienced matrix leader and decision maker with strong leadership skills to influence and motivate Teams
    • You have an understanding of contemporary translational research tools, including imaging, biomarkers and an understanding of unmet medical needs in oncology and ability to think beyond current paradigms of care
    • You have an analytical thinking and a high level of business awareness
  • Who we are
    The Roche Innovation Center Zurich (Roche Glycart AG) is active in the research and development of engineered therapeutic antibodies, with a focus on the fields of cancer immunotherapy.Part of the Roche Group since 2005, it currently employs about 140 people. Read more.

    Roche is an equal opportunity employer.
  • Job facts
    • Location Switzerland, Zurich, Zurich | Switzerland, Basel-Town, Basel
    • Function Research
    • Subfunction Early Development/ Translational Medicin
    • Schedule Full-time
    • Job level Team Leader
    • Job type Regular Employee
    • Division Roche Pharmaceuticals
    • Posted since 2017/11/24
    • Job-ID 3421746647
  • Get in touch
    Mathieu Vetter +41 61 688 41 00

    Work location: Basel or Zurich