45 days ago on roche.com

Senior Biostatistician, Translational Biomarkers

Roche AG

  • Work region
  • Sector
  • Employment type
  • Position

 Please refer to JobSuchmaschine in your application

Senior Biostatistician, Translational Biomarkers

Senior Biostatistician, Translational Biomarkers

Switzerland, Basel-Town, Basel

We are seeking a senior biostatistician to work on early clinical portfolio projects with a deep biological understanding primarily in the areas of Ophthalmology and Rare Diseases. The position requires proficiency in analyzing various types of biomarkers. As member of the Pharmaceutical Sciences Department of Roche Pharma (pRED) you will integrate a team of data analysis experts who performs statistical and bioinformatics analyses for discovery/validation of new targets and biomarkers, monitoring drug effects, as well as elucidating the mechanism behind diseases. In this role you will:

  • Provide biostatistics expertise to internal R&D projects and collaborate with external colleagues (consortia, academics, CRO)
  • Perform the design of experiments, power analysis and development of statistical analysis plans, general exploratory data analysis and statistical modeling (analysis of in vitro-, bioassay- and longitudinal data in particular), analysis of high dimensional data (genetics / genomics / proteomics / digital biomarkers)
  • Present analysis results and provide interpretation to scientists and management
  • Maintain and expand expertise in various statistical methods and computing tools to use internal and external data sets to drive decisions
  • Contribute to biomarker strategies enabling and supporting effective implementation of personalized medicines with major focus on Ophthalmology and Rare Diseases drug discovery/development projects, in cooperation with preclinical and early clinical project teams

  • Who you are
    You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point.

    You have a PhD in Biostatistics or a related discipline with at least 3 years of pharmaceutical industry experience. Combined with your leadership qualities in influencing and improving drug discovery by identifying, developing, and applying new quantitative methods you also bring a multidisciplinary skill set (biostatistics, programming, bioinformatics) with hands-on experience in omics data analysis and in biological interpretation of high throughput data (network and signature analyses). Furthermore you have:

    • Large experience in exploratory data analysis (e.g. PCA, clustering, supervised/unsupervised classification) and expertise in statistical and predictive modelling
    • Expert knowledge of R and familiarity with other programming languages such as SAS, Java and or Python is highly desirable
    • Understanding of regulatory guidelines in pharmaceutical research and early development setting and clinical development processes
    • Good Project management skills and ability to multi-task and work in a dynamic environment
    • Strong communication skills and ability to collaborate effectively with biologists, clinical scientists and software developers/IT in interdisciplinary and multinational teams, requiring fluent spoken English and adequate presentation skills

  • Who we are
    Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 8,500 people from approximately 90 countries work in Basel, which is one of Roche`s largest sites. Read more.

    Roche is an equal opportunity employer.
  • Job facts
    • Location Switzerland, Basel-Town, Basel
    • Function Research
    • Subfunction Modelling & Simulation
    • Schedule Full-time
    • Job level Individual Contributor
    • Job type Regular Employee
    • Division Roche Pharmaceuticals
    • Posted since 2017/11/01
    • Job-ID 3426470703
  • Get in touch
    Sabine Wehren +41 61 688 84 62

    Work location: Basel