39 days ago on roche.com

RiSE - Roche internship for Scientific Exchange - in Discovery Ophthalmology (9 months)

Roche AG

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RiSE - Roche internship for Scientific Exchange - in Discovery Ophthalmology (9 months)

RiSE - Roche internship for Scientific Exchange - in Discovery Ophthalmology (9 months)

Switzerland, Basel-Town, Basel

The position will be part of a cross functional team within Roche that includes members from the Discovery and Translational Medicine Group in Ophthalmology and from Pharmaceutical sciences. The main aim of this group is the discovery of novel Biomarker to support our translational efforts for one of our projects in which we aim to treat ophthalmic complications of diabetes in the eye, that include Diabetic macular edema and/or diabetic retinopathy.

 

The RiSE program (Roche Internships for Scientific Exchange) offers the most talented students the opportunity to enhance their competencies and to gain valuable work experience in this area of translational medicine with us.

 

All stakeholders are located in Basel, Switzerland.  In order to understand disease pathomechanism of disease and to identify associated biomarkers we are using and continuously evaluating novel cutting edge genetic, molecular and imaging methodologies.

 

The successful candidate will be part of these efforts to establish, evaluate and apply a novel, very sensitive sequencing technology called transient transcriptome sequencing (tt-Seq) that allows characterizing immediate transcriptional responses of cells with a high temporal resolution of minutes and apply this to human cells and disease models available in house.

 

During the internship your tasks will include: 

 

  • Be part of a cross functional team from ophthalmology discovery, translational medicine and pharmaceutical sciences working on the discovery of novel biomarkers and mechanism of action in Ophthalmology
  • You will be jointly mentored by experts in biomarker discovery, early pre-clinical drug development, in genetics and genomics methodology and bioinformatics
  • You will work with human blood as well as samples derived from diabetic animal models
  • You mechanistically evaluate the role of vascular versus inflammatory mechanisms contributing to disease.

 

  • Who you are
    You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point.

    You are someone who wants to influence your own development. You are looking for a company where you have the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point.

     

     

    Moreover you are/have:

    • Enrolled in PhD or medical degree program at a university
    • You have relevant experience in molecular biology and handling of human blood
    • Bring relevant cell culture experience, including the cultivation of primary cells from humans and animals as well as experience in cell separation and analysis methodology (e.g.  MACS sorting & FACS) as well as functional assays in inflammation (e.g. migration assays)
    • Relevant knowledge in ophthalmology/neuroscience and handling of large data sets is of advantage
    • Expertise in state of the art  Next Generation Sequencing technologies and genomic data handling is a plus

     

    Information about application documents and start date: The preferred start date of the internship is [Early 2018] or upon availability.

     

    The intention is to find a mutual beneficial and ideally complementary approach for collaboration in the space of Neuroinflammation in Ophthalmology, thus, please explain in a cover letter your particular interest in this area.

     

    Applications need to include a CV and a cover letter, as well as a letter from your academic supervisor supporting your RiSE application.

     

    Please note that non-EU/EFTA nationals have to successfully apply for a Swiss work permit.

  • Who we are
    Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 8,500 people from approximately 90 countries work in Basel, which is one of Roche`s largest sites. Read more.

    Roche is an equal opportunity employer.
  • Job facts
    • Location Switzerland, Basel-Town, Basel
    • Function Research
    • Subfunction Other Research
    • Schedule Full-time
    • Job level Entry Level
    • Job type Internship / Student
    • Division Roche Pharmaceuticals
    • Posted since 2017/12/13
    • Posted until 2018/01/12
    • Job-ID 3426017404
  • Get in touch
    Finkbeiner, Jasmin +41 61 688 2972