35 days ago on roche.com

Head of Translational Science, Research and Early Development Oncology

Roche AG

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Head of Translational Science, Research and Early Development Oncology

Head of Translational Science, Research and Early Development Oncology

Switzerland, Zurich, Zurich

Switzerland, Basel-Town, Basel

The Head of Translational Science in Pharma Research and Early Development (pRED) Oncology acts as the leads a team of experts who act as representatives for the Translational Medicine Group and provides leadership and input on strategy and clinical development aspects for the portfolio of internal projects in pre-clinical development and external projects evaluated by external innovation processes.


Key responsibilities:

  • Member of the Oncology Translational Medicine-Leadership Team:

- Generate a clinical vision for the programs

- Ensure consistency of early clinical plans (content, presentation, scientific approaches) with the overall Translational Medicine and Oncology Development and Therapeutic Area (DTA) strategy

- Ensure preclinical plans are fully aligned with the early clinical plans

  • Provides leadership and scientific expertise globally for the therapeutic area and participates in new initiatives to sustain long term Roche leadership in the Oncology DTA
  • Acts as core member and reviewer in the development review committee, DTA-Portfolio Committee, and Oncology Research Review Committeeand represents the Translational Science group on relevant internal decision and governance bodies
  • Provides review and input to internal and external significant scientific/preclinical presentations and documents  
  • Contribute to overall Translational Medicine strategy, vision and project prioritization
  • Contribute to external innovation and partnering strategy by defining the needs


  • Who you are
    You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point.
    • PhD or MD, preferred, with at least 6-8 years in the pharmaceutical industry or equivalent level of experience with demonstrated record of clinical development of early compounds in a results-oriented manner
    • Has demonstrated strong leadership skills in managing multidisciplinary teams
    • Demonstrated in depth knowledge of the scientific data (discovery and clinical) and landscape of early Oncology Development
    • Excellent communication and interpersonal skills
    • Strategic, visionary skills
    • Strong influence management skills; able to navigate a complex organization effectively and efficiently and impact decisions positively in a matrix environment
    • Ability to resolve conflicts and adapt to change
    • Willingness to travel internationally and work across cultures
  • Who we are
    The Roche Innovation Center Zurich (Roche Glycart AG) is active in the research and development of engineered therapeutic antibodies, with a focus on the fields of cancer immunotherapy.Part of the Roche Group since 2005, it currently employs about 140 people. Read more.

    Roche is an equal opportunity employer.
  • Job facts
    • Location Switzerland, Zurich, Zurich | Switzerland, Basel-Town, Basel
    • Function Research
    • Subfunction Early Development/ Translational Medicin
    • Schedule Full-time
    • Job level Manager with Direct Reports
    • Job type Regular Employee
    • Division Roche Pharmaceuticals
    • Posted since 2017/11/13
    • Job-ID 2968149835
  • Get in touch
    Mathieu Vetter +41 61 688 41 00