15 days ago on idorsia.com

Scientist Chemistry

Idorsia Pharmaceuticals Ltd

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Scientist Chemistry

Job Description

Job Title: Scientist Chemistry

Job ID: DD1811

Posting Date: 07.02.2018

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About Idorsia Pharmaceuticals Ltd
Idorsia Ltd is reaching out for more - We have more ideas, we see more opportunities and we want to
help more patients.

In order to achieve this we will develop Idorsia into one of Europe’s leading biopharmaceutical company,
with a strong scientific core.

Headquartered in Switzerland - a European biotech hub - Idorsia is specialized in the discovery and
development of small molecules, to transform the horizon of therapeutic options. Idorsia has a broad
portfolio of innovative drugs in the pipeline, an experienced team, a fully-functional research center,
and a strong balance sheet – the ideal constellation to bringing R&D efforts to business success.

Idorsia was listed on the SIX Swiss Exchange (ticker symbol: IDIA) in June 2017 and has over 600 highly
qualified specialists dedicated to realizing our ambitious targets.

Scientist Chemistry

Job Responsibilities

  • Design and synthesize novel compound series interacting with a given biological target
  • Perform reactions on laboratory scale (mg to multi g) according to known procedures
  • Synthesis of single compounds and small compound libraries using parallel chemistry techniques
    and equipment
  • Monitor reaction progress using TLC, LC-MS, etc.
  • Interpret reaction monitoring data and take appropriate action
  • Purification of reaction products using standard techniques e.g. (automated) column
    chromatography, prep. HPLC, crystallization or distillation
  • Perform compound analysis (e.g. TLC, LC-MS, NMR, etc.)
  • Interpret analytical data and take appropriate action
  • Document practical work using electronic lab journal
  • Closely follow development of scientific area (literature)
  • Routinely evaluate and, if appropriate, implement latest developments to ensure in house
    facilities are at state of the art
  • Plan practical work on long term basis, give timelines of own work
  • Look for alternative reaction conditions, optimize reaction process
  • Propose alternative synthesis pathways
  • Drive SAR of own compound series
  • Present own work at group meetings, at larger internal meetings (e.g. CCB, PUM) and at external
  • Interact and communicate with interdisciplinary DD team
  • Write patents and scientific publications

Candidate’s Requirements

  • PhD and PostDoc in synthetic organic chemistry

  • Knowledge of field specific software/data bases (e.g. ChemDraw, SciFinder, Reaxys,
    computational chemistry tools)

  • Well-organized, flexible in work assignment and work schedule

  • Hands-on attitude and ability to work efficiently and independently

  • High level of creativity

  • Excellent communication skills
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  • Ability to work in multidisciplinary team

  • Fluent in English and German or French

  • Problem solving and play to win attitude

  • Resilient, resistant to time pressure

What Idorsia offers

  • Exciting opportunities for development and professional growth within our dynamic organization
  • A collaborative and solution oriented enviroment where you can make a difference
  • An innovative and open culture in a truly multicultural environment
  • A competitive salary and generous social benefits

Data Privacy

By applying you signify you have read and agreed our Data Privacy Policy which is available on our
WebSite at the following page: https://www.idorsia.com/careers/faq/privacy-policy

Work Location: Allschwil
Country: Switzerland
Business Unit/Division/Department: Drug Discovery Chemistry
Schedule: Fulltime
Job Type: Permanent

If you are interested, please send your CV and motivation letter by email to
idorsia.careers@idorsia.com clearly stating the job title and reference of the position to which you are
applying in the subject line.

Please be informed that if you are selected for this position, your employment will be subject to a pre-
employment background screening process, of which you would be informed in greater detail in due

Please note Idorsia operates a strictly-controlled list of preferred recruitment partners. For those
partners who have no valid, signed Master Service Agreement in place with Idorsia all unsolicited
resumes, CVs, anonymous profiles, or any other candidate details submitted through our website or to
personal e-mail accounts of employees of Idorsia Pharmaceuticals (including any of its subsidiaries,
affiliates or related companies) are considered the property of Idorsia Pharmaceuticals and are not
subject to payment of any form of introduction, placement or referral fees.

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